Chemotherapy drugs slow cancer growth says a recent study from Johns Hopkins University School of Medicine. Chemotherapy drugs are being used for many years to treat Cancer. But recently a research team lead by Gregg L. Semenza (director of the vascular program at the Johns Hopkins Institute for Cell Engineering) have revealed how Chemotherapy drugs work in treating Cancer.
More than 3,000 FDA-approved drugs were used for testing by the team. They found that a drug by the name Daunorubicin reduced HIF-1's gene-activating ability by more than 99 percent.For further analysis, the team grew tumors in mice from human prostate cancer cells. They treated these mice with Daunorubicin, Doxorubicin or Saline once a day for 5 days and measured tumor size. They found that tumors in saline-treated mice nearly doubled in size in that time, whereas tumors in the drug-treated mice stayed the same size or became smaller.
More than 3,000 FDA-approved drugs were used for testing by the team. They found that a drug by the name Daunorubicin reduced HIF-1's gene-activating ability by more than 99 percent.For further analysis, the team grew tumors in mice from human prostate cancer cells. They treated these mice with Daunorubicin, Doxorubicin or Saline once a day for 5 days and measured tumor size. They found that tumors in saline-treated mice nearly doubled in size in that time, whereas tumors in the drug-treated mice stayed the same size or became smaller.
0 comments:
Post a Comment